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Premium Omega-3
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60 Softgels
60 Softgels
3 Bottles (SAVE 33%)
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Customer Rating: 32 Reviews

... Our fish oil features patented VESIsorb® technology - One Premium Omega-3 softgel delivers a dose of EPA/DHA equivalent to six regular fish oil capsules ...
Premium Omega-3 is one of the highest percentages of natural omega-3 fatty acids available without a prescription. The natural triglyceride form is the type of omega- 3 found in the foods we eat. Premium Omega-3 features VESIsorb®, providing a 567% increase in absorption and greater bioavailability compared to regular fish oil capsules. One Premium Omega-3 softgel delivers a dose of EPA/DHA equivalent to six regular fish oil capsules.
Why You Should Buy Premium Omega-3 (Fish Oil)

  • Fish Oil Promotes Healthy Skin*
  • The EPA in Fish Oil Supports Optimal Joint Function*
  • Omega 3 Fatty Acids From Fish Oils Support Important Cardiovascular Duties*
  • Omega-3's Found To Ease Symptoms Of PMS*
  • The DHA Contained In Fish Oil Is Important For Women During Pregnancy To Support A Baby's Brain & Beyond For Developing Children.
  • The Bottom Line: Our brand of fish oil features a natural form of beneficial omega-3's that are not treated with chemicals. This natural tryglyceride form is better absorbed by your body and better for you. The addition of VESIsorb® allows even better bioavailability, making Premium Omega-3 the highest potency natural fish oil available without a prescription.

Real Help From Real People, Online or by Phone
Unlike other companies on the web, we have healthcare professionals standing by to answer any product questions you may have. If you need information about the health benefits of omega-3's or fish oil dosage, please do not hesitate to call us (800) 860-9583 or Live Chat with us.

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The Premium Omega-3 Difference

  • Premium Omega-3 by Pure Prescriptions is a natural fish oil that contains VESIsorb® are BETTER ABSORBED - so they are BETTER FOR YOU.
  • The worldwide introduction of VESIsorb® for oral and topical applications represents the newest approach to improving lipid based bioactive absorption, including Omega-3 fatty acids. The technology was developed by Vesifact, Baar, Switzerland and is protected worldwide by over 40 patents and patents pending.
  • A pharmacokinetic pilot study in humans comparing OmegaChoice™ Omega- to the same OmegaChoice™ in the VESIsorb® delivery system demonstrated an increase of 567% in peak blood levels. The relative bioavailability calculated using the area under the curve was also increased by 487%.
  • The VESIsorb® technology has a "green" impact on the environment. By increasing bioactive absorption (like Omega-3 Fish Oils), this in turn reduces the number of soft gels needed per day to achieve blood plasma levels for optimum health and wellness. The efficient use of resources results in fewer bottles, less packaging waste and reduced transportation needs.

Omega 3 Fish Oil Testimonials

Did you know that most Americans do not get enough Omega-3s?

An adequate dietary supply of Omega-3s can play an important role in overall health throughout all stages of life. Consumers have looked to natural foods to derive a wide range of health benefits from omega-3 fatty acids. EPA and DHA omega-3 is significantly more bioavailable for absorption through cellular membranes found in fish oil than other sources, like flaxseed or borage. Premium Omega-3 fish oil provides EPA/DHA as a highly pure, stable product with less odor and fishy taste.


Find Fish Oil ReviewsPure Prescriptions has partnered with leaders in the fish oil industry to bring you Premium Omega-3. Pure Prescriptions is a leader in introducing new innovations and scientific technologies that help deliver health and wellness through natural products. We are relentless in our pursuit of quality and improvements in nutritional supplements that offer more and better solutions to the growing need for healthy and nutritious wellness options. Our dedicated team of global research partners invests heavily in research and development (R&D) and scientific studies. They also work closely with major universities, medical institutions, and clinical research organizations (CROs) to further ensure we have the newest developments keeping natural products on the cutting edge of the latest scientific discoveries.

Compelling examples of these innovations are technologies like the patented VESIsorb® naturally self-assembling association colloidal delivery system and oil to powder technology contained within our Premium Omega-3 fish oil softgels.


Our fish oil sources focuses on omega-3s in the natural triglyceride form, which is the form of omega-3 fatty acids naturally found in the food we eat. Produced in a Good Manufacturing Practice (cGMP) facility in Cincinnati, OH to pharmaceutical grade quality standards, our omega-3 EFAs contain the highest percent EPA and DHA as a triglyceride that is currently available in the global marketplace. Higher purity and better stability with less odor and fishy taste afford broader applications and benefits.

Fish oil supplements come in two forms: the natural triglyceride form or the synthetically manipulated ethyl ester form. It is worth knowing which form you are buying; it is usually not on the label, but you can inquire of the manufacturer.

In another study of women, the bioavailability of natural triglyceride type fish oil was double that of ethyl esters. Blood concentrations of EPA and DHA were 52 to 60 percent higher after taking natural triglyceride fish oil than after taking ethyl ester fish oil. “It's apparent that the ethyl ester form of EPA and DHA cannot mimic the physiological activity of natural fish oil in the form of triglycerides, at least in the liver, concluded a recent study on animals.”

The EPA and DHA omega-3 is significantly more bioavailable for absorption through cellular membranes found in fish oil than from flaxseed oil or borage oil. In fact, vegetable oils such as flax and borage do not contain any naturally occurring EPA or DHA at all. Instead, they contain the fatty acid alpha-linolenic, which converts to EPA and DHA when ingested. The conversion, however, is poor at only 4-6%, and is dependent on an individual’s diet and state of wellness.

For more information about this difference, read Dr. Larson's report on natural tryglyceride fish oil with VESIsorb®.
Premium Omega-3: Fish Oil the Way Nature Intended

Clinical Science:

A pharmacokinetic study (single oral dose, crossover) in humans comparing OmegaChoice® Omega-3 EPA to the same OmegaChoice® in the VESIsorb® delivery system demonstrated an increase of 567% in peak blood levels (cmax) of EPA. The relative bioavailability calculated using the area under the curve (AUC0-12h) was also increased by 487%.

According to the renowned Mayo Clinic and the American Heart Association, evidence suggests that recommended amounts of the Omega-3 fatty acids slow the buildup of plaque (“hardening of the arteries”), lower triglycerides, and supporting healthy blood pressure thereby reducing the risk factors of heart disease.

Omega 3 Comparison ChartResearch has demonstrated that omega-3 fatty acids are beneficial for cardiovascular health and reduced risk of cardiovascular disease, and are linked to benefits associated with joint mobility, brain health, fetal development, improved behavior/mood, and anti-aging.

More than 75 studies have demonstrated the effectiveness of Omega-3 for supporting healthy triglyceride levels. Numerous studies have shown that Omega-3 in the triglyceride form are better absorbed and more bioavailable, and OmegaChoice® contains the highest percent EPA and DHA as a triglyceride currently available in the global marketplace.

Population studies support the value of omega-3. Data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study found

increased adherence to a Mediterranean diet among 2,671 adults with heart attacks lowered mortality rate by 18 percent. A September 2008 Italian study found that daily supplements of omega-3 fatty acids reduced deaths and hospitalizations of people with heart failure. Similar findings were reported by Dutch researchers, who found among adults with previous heart attack, following a Mediterranean diet, along with moderate alcohol consumption and not smoking, lowered all-cause mortality by 40 percent. A study in Diabetes found that omega-3 from fish oil improves glucose uptake in the presence of insulin.


Singh. Essential fatty acids, DHA and the human brain. Indian Journal of Pediatrics. 2005; 72(3):239–42.
Peet, et al. Two double–blind placebo–controlled pilot studies of eicosapentaenoic acid in the treatment of schizophrenia. Schizophr Res. 2001; 49(3):243–251.
Peet, Horrobin, et al. A dose–ranging study of the effects of ethyl–eicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Archives of General Psychiatry. 2002; 59:913–919.
James, et al. Dietary n–3 fatty acids and therapy for rheumatoid arthritis. Semin Arthritis Rheum. 1997; 27:85–97.
Puri, et al. The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2004; 70:399–401.
Theodoratou, et al. Dietary fatty acids and colorectal cancer: a case–control study. American Journal of Epidemiology. 2007; 166(2):181–195.
Terry, et al. Increased fatty fish consumption may reduce prostate cancer risk. Lancet. 2001; 357(9269):1764–1766.
Volker, et al. Efficacy of fish oil concentrate in the treatment of rheumatoid arthritis. J Rheumatol. 2000; 27:2343–2346.
Cleland, et al. The role of fish oils in the treatment of rheumatoid arthritis. Drugs. 2003; 63:845–853.
Frangou, et al. Efficacy of ethyl–eicosapentaenoic acid in bipolar depression: randomised double–blind placebo–controlled study. British Journal of Psychiatry. 2006; 188:46–50.
Zanarini, et al. Omegan–3 Fatty Acid Treatment of Women With Borderline Personality Disorder: A Double–Blind, Placebon–Controlled Pilot Study. Journal of Clinical Psychiatry. 2003; 160:167n–16.
Genuis, et al. Time for an oil check: the role of essential omegan–3 fatty acids in maternal and pediatric health. Journal of Perinatology. 2006; 26(6):359n–65.
Gelder, et al. Fish consumption, n–3 fatty acids, and subsequent 5n–y cognitive decline in elderly men: the Zutphen Elderly Study. American Journal of Clinical Nutrition. 2007; 85:1142n–7.
Hibbeln, et al. Annual Meeting of the American Psychiatric Association; San Francisco. 2003.
Denburg, et al. Fish oil supplementation in pregnancy modifies neonatal progenitors at birth in infants at risk of atopy. Pediatric Research. 2005; 57(2):276–81.
Silvers, et al. Randomised double–blind placebo–controlled trial of fish oil in the treatment of depression. Prostaglandins Leukot Essent Fatty Acids. 2005; 72(3):211–8.
Zampelas, et al. Fish Consumption Among Healthy Adults Is Associated With Decreased Levels of Inflammatory Markers Related to Cardiovascular Disease. Journal of the American College of Cardiology. 2005; 46:120n–124. (ATTICA).
Sinn, et al. Effect of supplementation with polyunsaturated fatty acids and micronutrients on learning and behavior problems associated with child ADHD. Journal of Developmental & Behavioral Pediatrics. 2007; 28(2):82–91.


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Supplement Facts:

Suggested Use: As a dietary supplement, take 1-2 softgels daily with food or as directed by your healthcare professional or pharmacist. Keep tightly closed in a cool, dry place in the original container. Do not expose to excessive heat. Keep out of reach of children.

Two Softgels Contain:

Ingredients AMT %DV
Serving Size 2 Softgels - -
Servings Per Container 30-60 - -
Calories 8 -
Calories from Fat 8 -
Total Fat 0.8 g <1%
Saturated Fat 0 g 0%
Trans Fat 0 g -
Vitamin D (as cholecalciferol D3) 2000 IU -
OmegaChoice® TG Omega-3 - -
Essential Fatty Acids 840 mg -
EPA (Eicosapentaenoic Acid) as Triglyceride 80 mg -
DHA (Docosahexaenoic Acid) as Triglyceride 480 mg -
Other Omega-3 Fatty Acids as Triglyceride 620 mg -
Astaxanthin (as AstaREAL) 600 mcg -

Other Ingredients: Fish Oil Concentrate (anchovy), Gelatin, Glycerin (softgel capsule), Medium Chain Triglycerides, Nonionic Surfactant, Sucrose, Sucrose Fatty Acid Esters, Natural Annato Color

(-) There is no %DV or the manufactuer has not provided this data.
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5 star rating5 star rating5 star rating5 star rating5 star rating Premium Omega-3, 6/19/2016
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5 star rating5 star rating5 star rating5 star rating5 star rating Premium Omega-3, 9/18/2015
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making sure my cholesteroal and triglyceride in the normal level
5 star rating5 star rating5 star rating5 star rating5 star rating Premium Omega-3, 9/2/2015
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I'll let you know when I get my blood test results
5 star rating5 star rating5 star rating5 star rating5 star rating Premium Omega-3, 7/25/2015
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I use this product to help control inflammation for severe allergies. This product works so well I do not even take my daily antihistamines anymore! I can't say enough about this...
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5 star rating5 star rating5 star rating5 star rating5 star rating Premium Omega-3, 11/11/2014
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I take these daily although I haven't been using them for a long period of time. I recommend them to anyone looking for a quality Omega-3 supplement. Another quality product from Pure...
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*These statements have not been evaluated by the FDA. Products are not intended to diagnose, treat, cure or prevent any disease.
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