Carlsbad, CA IAGEN Biologics, Inc., a privately-owned developer and marketer of therapeutic dietary supplements introduces Cardiokinase™, the new platinum standard for the fibrinolytic enzyme, nattokinase. There was an announcement last week that Cardiokinase (Nattokinase-CK) will be the recipient of the 2009 Nutritional Business Journal Product Merit Award.
In 1980, Dr. Hioryuki Sumi discovered that “natto,” a traditional fermented food in Japan, possesses previously unidentified thrombolytic activity which is characterized by the unique ability to dissolve blood clots. Because the isolated enzyme has very strong thrombolytic activity, similar to that of urokinase and plasmin, the enzyme was named nattokinase.
Although nattokinase is not new to the marketplace, there is a new strain that exhibits some exceptional improvements over the original. It should be appropriate then that Dr. Sumi himself set the new bar with the scientific development on this new substance. We will highlight some of the key advancements. This will clearly delineate Cardiokinase (CK) from any other nattokinase on the market.
CK utilizes a new standardization for fibrinolytic activity which is more sensitive and specific to nattokinase activity. Originally, the Fibrin Unit (FU) method was created for the sake of convenience but with some advancements in the understanding of enzyme activity, a new more comprehensive method is the clear choice for maximum potency. Therefore, to accurately measure the potency of CK, International Units (IU) are required to quantify the results of the enzyme activity. When this new standardized method is used to compare the effectiveness with other nattokinase products on the market, Cardiokinase is in a class of its own.
Cardiokinase incorporates a new strain (“strain N”) of Bacilius Substilisin that produces higher activity than other strains. In particular, the cultured solution of the CK (N strain), displayed activity that was 17.9 times greater that of the control. The therapeutic benefit of this type of activity on human cells is the promotion of the release of tissue-plasminogen activator (t-PA). t-PA is a protein involved in the breakdown of blood clots – it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown.
In addition to t-PA, CK has demonstrated a new mechanism of action involving fibrinolytic pharmacokinetics. This new strain of nattokinase has shown for the first time that is has a higher kinin-producing capacity than plasma kininogen. When a kinin-producing enzyme is activated, it produces bradykinin and other substances in the blood, like kallikrein. The physiological activities of kinin include lowering blood pressure, promotion of capillary permeability, promotion of lymph flow, and inflammatory modulation. The kinins act locally to induce vasodilation and contraction of smooth muscles. The kinin-kallikrein system also plays a role in coagulation and pain. This kinin-producing activity is involved in the circulatory systems of all internal organs.
Another novel characteristic of Cardiokinase is its “anti-viscogenic effect”. No other natural substance has demonstrated the ability to quantitatively lower whole blood viscosity as CK has. As the viscosity goes down there is less resistance for the blood to flow through the blood vessels. The applications of this attribute alone make CK one of the most versatile natural supplements available.
Finally, unlike other commercial sources of nattokinase, Cardiokinase incorporates a non-corn source of maltodextrin, making it the most hypoallergenic source of nattokinase on the market. Furthermore, the soybeans used in the production of Cardiokinase come from an organic, non-GMO farm located right here in the U.S.A.
About IAGEN Biologics
IAGEN Biologics represents the latest scientific research from around the globe, coupled with the insight and knowledge of our health care professionals to deliver the highest quality, potency, and efficacy available anywhere. Every product is delivered to you with our personal guarantee that you will feel the difference.
Cardiokinase™ retails for $75 for a 30-day supply and
is available at the Pure Prescriptions website at www.pureprescriptions.com Founded in California by Dr. Devin Ryerson in 2001, IAGEN Biologics a division of Pure Prescriptions
is committed to providing sound advice, practical health knowledge
and premier health products. For more information, product
samples or schedule an interview with Dr. Chad Larson please
contact via Email.
For more Cardiokinase information, nattokinase science and studies, nattokinase history, please visit the
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