What Makes Cardiokinase The Best Nattokinase? 
Cardiokinase contains a new kind of Nattokinase even more potent than the original (NSK-SD®). Cardiokinase incorporates a new strain (“strain N”) of Bacilius Substilisin that produces higher activity than other strains. This new nattokinase and is the strongest and safest nattokinase available.

Cardiokinase contains an unprecedented high activity of nattokinase, more than 200% the effectiveness of other nattokinase products. Simply put, if it's not Cardiokinase, you're not getting the best.

So when it's difficult to tell the difference between one nattokinase and another, trust the one that's been tested, proven and is more effective.

"Cardiokinase has literally created a new standard for the nattokinase market. The bar is raised so high that such an achievement can only be accomplished by the researcher who discovered the original nattokinase, Dr. Sumi. It should be appropriate that Dr. Sumi himself did all the scientific development of this new substance in Cardiokinase and the only nattokinase on the market that has his stamp of approval."

-Dr. Chad Larson
Director of Nutrition, Pure Prescriptions, Inc.

What is Cardiokinase™?
Award Winning Cardiokinase features a new patented nattokinase. Nattokinase is an enzyme that is extracted from the traditional Japanese soy food called "natto." Nattokinase was first discovered by Dr. Hiroyuki Sumi, PhD. Natto has been used traditionally to support cardiovascular health. Modern research has revealed that nattokinase works by breaking down fibrin, a protein involved in clotting of the blood.*

For anyone considering purchasing nattokinase, it is very important to know that all nattokinase is not created equal. There are many less expensive brands of so called nattokinase on the market and through the internet, however, it is important to realize that these have been found to be completely ineffective by laboratory research.

It's essential that nattokinase doesn't include Vitamin K in order to prevent an adverse interaction with drugs such as Coumadin®. Thus, our patented process extracts all traces of Vitamin K. Cardiokinase (Nattokinase Strain N) studies have confirmed the safety. Cardiokinase contains an unprecedented high activity of nattokinase, over 200% the effectiveness of other nattokinase products. Simply put, if it's not Cardiokinase, you're not getting the best.

So when it's difficult to tell the difference between one nattokinase and another, trust the one that's been tested, proven and is most effective.

1. Cardiokinase™ (CK)utilizes a new standardization for fibrinolytic activity which is more sensitive and specific to nattokinase activity. Originally, the Fibrin Unit (FU) method was created for the sake of convenience. Because fibrin, which is insoluble in water, is used as the substrate, accurate measurement of the enzyme reaction is not possible through this method. Therefore, to accurately measure the potency of CK, International Units (IU) are required to quantify the results of the enzyme activity.

2. Cardiokinase incorporates a new strain (“strain N”) of Bacilius Substilisin that produces higher activity than other strains. In particular, the cultured solution of the CK (N strain), displayed activity that was 17.9 times greater that of the control. Furthermore, fibrinolytic activity was also observed in the bacteria itself, and the activity on the N strain elevated to a level that was 70 times as much as the control. The therapeutic benefit of this type of activity on human cells is the promotion of the release of tissue-plasminogen activator (t-PA). t-PA is a protein involved in the breakdown of blood clots – it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown.

3. In addition to t-PA, CK has demonstrated a new mechanism of action involving fibrinolytic pharmacokinetics. This new strain of nattokinase has shown for the first time that is has a higher kinin-producing capacity than plasma kininogen. The physiological activities of kinin (and its products like bradykinin) include lowering blood pressure, promotion of capillary permeability, local vasodilation, smooth muscle contraction, promotion of lymph flow, and inflammatory modulation. This kinin-producing activity is involved in the circulatory systems of all internal organs.

Cardiokinase's hypotensive and circulation-improving effects have the potential to replace other more invasive and ADR-promoting medications in the conventional and alternative marketplace.

4. Another novel characteristic of CK is its anti-viscogenic effect. No other natural substance has demonstrated the ability to quantitatively lower blood viscosity as CK has. The applications of this attribute alone make CK one of the most useful therapies in even the most serious cardiovascular conditions.

5. Lastly, unlike other commercial sources of nattokinase, Cardiokinase incorporates a non-corn source of maltodextrin, making it the most hypoallergenic source of nattokinase on the market.

The advantages of improved circulation are self-evident. Applications for CK can be elucidated paying special consideration to its fibrinolytic activity and anti-viscogenic effect. From cosmetics to heart and brain health, improved blood flow is a ubiquitous benefit for the human body.