Suggested Use: 1–2 capsules per day, in divided doses, with meals.
B12 Folate -
Pure Encapsulations offers B12 Folate, combining these two powerhouse B vitamins. B12 and folate work together to support the nervous system, cardiovascular system and is crucial for fetal neural development. This product feature Metafolin. An extensive body of evidence indicates that adequate folate intake may provide significant cardiovascular, cellular and neural protection. However, genetic variations affecting activation and metabolism of supplemental folic acid are highly prevalent. In line with our commitment to consistently offer innovative, science-based ingredients, Pure Encapsulations has updated a number of products†, including our multivitamins, to provide Metafolin® (L-5-MTHF). Metafolin® is a naturally occurring, universally metabolized and active form of folate, L-5-MTHF. As such, it can be directly used in a diverse array of essential methylation reactions to support cardiovascular, neural and emotional health. Additionally, clinical evidence indicates that the bioavailability of Metafolin® is superior to folic acid. In a double-blind, randomized, placebocontrolled intervention study of 144 women of child-bearing age, 5-MTHF supplementation resulted in a greater accumulation of 5-MTHF in red blood cells than equimolar doses of folic acid.
B12 Folate provides optimum support for the GI tract, nervous system, and the metabolism of fats and protein.
What Is It?
B12 Folate is a combination of two water-soluble
B vitamins, folic acid and vitamin B12. Folic acid is provided
in this formula as Metafolin®, the naturally occurring
universally metabolized form of folate. Metafolin® is
chemically identical to the active folate metabolite,
5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF is the
predominant, naturally occurring form of folate in food.
Through bypassing several enzymatic activation steps,
it is directly usable by the body and provides all of
the benefits of folic acid regardless of functional or
genetic variations. The B12 in this formula is provided
as methylcobalamin, the most bioavailable form of this
vitamin.*
Uses For B12 Folate
Nutrient Metabolism: Folic acid and vitamin B12 are
interrelated in function. They convert carbohydrates
into energy and are vital in the metabolism of fats and
protein. They play an important role in the maintenance
of muscle tone in the GI tract and the integrity of skin,
hair and the liver. They are also critical for maintaining
red blood cell homeostasis and healthy homocysteine
levels.*
Nervous System Health: Adequate folate status is critical
for nucleic acid synthesis and neurotransmitter synthesis.
At the molecular level, the main function of folate is
to donate methyl groups in key biochemical reactions
occurring in blood cells, neurons, the vasculature and
many other tissues. In recent studies, methylcobalamin
has demonstrated an enhanced ability to support
neurological function. Vitamin B12 promotes protein
synthesis for maintaining healthy nerve cells and myelin.
Methylcobalamin may also help to moderate levels of
glutamate in the brain, encouraging healthy brain
cell activity, as well as memory, mood, and cognitive
function. In general, vitamin B12 works with folate to
promote DNA and red blood cell health.*
What Is The Source?
Metafolin®, L-5-methyltetrahydrofolate (L-5-MTHF) is
synthetic. Methylcobalamin is produced from corn
dextrose fermentation. Hypo-allergenic plant fiber is
derived from pine cellulose. Vitamin C (ascorbyl
palmitate) is derived from corn dextrose fermentation and
palm oil.
Metafolin® is a registered trademark of Merck KGaA,
Darmstadt, Germany.
Are There Any Potential Side Effects Or
Precautions?
At this time, there are no known side effects or precautions.
If pregnant or lactating, consult your physician before
taking this product.
Are There Any Potential Drug Interactions?
Folic acid may adversely interact with chemotherapeutic
drugs.
Ask The Doctor - Heart DiseaseMy Father passed away from a heart attack. I'm worried I might be going down the same road. Can you give me some suggestions on ways of preventing heart disease?
Cardiovascular Disease OverviewCardiovascular disease is the number one cause of death in the United States. This introductory article briefly discusses several diseases that have a role in the development of cardiovascular disease.
Pure Q10®
Digestive Defense
